Abocal Effervescent Tablets 10’s-Potential Overview

Brand Name: Abocal
Active Ingredients: Calcium Carbonate, Vitamin D3 (Cholecalciferol)

For the General Public:

1. Uses:
   • Abocal is used for the prevention and treatment of calcium and vitamin D deficiencies.
   • It supports bone health, prevents osteoporosis, and helps maintain normal calcium levels in the body.
2. Dosage:
   • Dissolve one effervescent tablet in a glass of water.
   • Take once daily or as directed by your healthcare provider.
3. Possible Side Effects:
   • Common side effects include nausea, constipation, or flatulence.
   • Seek medical attention for signs of an allergic reaction or unusual symptoms.
4. Important Information:
   • Avoid if you are allergic to calcium, vitamin D3, or any excipients in the product.
   • Consult your doctor before use if pregnant, breastfeeding, or on other medications.
   • Do not exceed the recommended dose.

For Pharmacists:

1. Medicine Name: Abocal Effervescent Tablets
2. Brand Name: Abocal
3. Active Ingredient(s):
   • Calcium Carbonate: 1250 mg (providing 500 mg of elemental calcium).
   • Vitamin D3: 200 IU.
4. Indications:
   • Management of calcium and vitamin D deficiencies.
   • Adjunct in osteoporosis treatment to improve bone mineral density.
   • Supportive therapy in conditions like osteomalacia and hypocalcemia.
5. Pharmacodynamics:
   • Mechanism of Action:
     • Calcium Carbonate replenishes calcium levels required for bone mineralization, muscle function, and nerve signaling.
     • Vitamin D3 facilitates intestinal absorption of calcium and phosphorus and regulates calcium homeostasis.
   • Pharmacological Effects:
     • Improves bone strength and density.
     • Helps maintain optimal serum calcium levels.
6. Pharmacokinetics:
   • Absorption: Calcium is absorbed primarily in the small intestine, with better absorption in acidic conditions.
   • Distribution: Widely distributed, mostly stored in bones and teeth.
   • Metabolism: Vitamin D3 is converted into its active form (calcitriol) in the liver and kidneys.
   • Elimination: Excess calcium is excreted through feces; vitamin D metabolites are eliminated via bile.
7. Receptor Binding (if applicable):
   • Vitamin D binds to vitamin D receptors in the intestines to stimulate calcium and phosphorus absorption.
8. Dosage and Administration:
   • Adults: One effervescent tablet daily, dissolved in water.
   • Pediatric: Use only under medical supervision.
9. Contraindications:
   • Hypercalcemia or hypercalciuria.
   • Severe renal impairment or kidney stones.
10. Warnings and Precautions:
    • Use cautiously in patients with renal impairment or cardiovascular disorders.
    • Avoid taking with high-dose antacids or other calcium supplements.
11. Drug Interactions:
    • Reduced absorption with corticosteroids or high-dose antacids.
    • Potential interaction with bisphosphonates, iron supplements, and certain antibiotics (e.g., tetracyclines).
12. Adverse Reactions:
    • Common: Gastrointestinal upset, nausea, or diarrhea.
    • Serious: Hypercalcemia, nephrolithiasis, or cardiac arrhythmias.

Storage:

• Store below 25°C in a dry place.

Packaging:

• Effervescent tablets, 10 per pack.

Conclusion:

1. Abocal is a convenient and effective supplement for addressing calcium and vitamin D deficiencies, essential for maintaining bone health and preventing related disorders.
2. Proper dosage and administration guidelines must be followed to minimize potential side effects.
3. Pharmacists should educate patients about the importance of avoiding excessive intake and monitoring interactions with other medications.